Cisplatin pubchem
WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the … WebThe chemotherapeutic cisplatin causes renal dysfunction and renal proximal tubular cell (RPTC) apoptosis. The goal of these studies was to examine the role of p53, caspase 3, 8, and 9, and mitochondria in the signaling of cisplatin-induced apoptosis. Cisplatin (50 microM) produced time-dependent apo …
Cisplatin pubchem
Did you know?
WebA stable, microcrystalline form of cisplatin, a process for its preparation, and stable, sterile dry-mix formulations thereof which are more rapidly reconstituted with sterile water to produce... WebCisplatin (cisPt) is one of the strongest anticancer agents with proven clinical activity against a wide range of solid tumors. Its mode of action has been linked to its ability to crosslink with the canonical purine bases, primarily with guanine. Theoretical studies performed at the molecular level suggest that such nonspecific interactions can also take …
WebAnastrozole C17H19N5 CID 2187 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. This application requires Javascript. Please turn on Javascript in order to use this application. WebJan 5, 2024 · Keywords: 5-Fluorouracil (PubChem CID: 3385); Carboplatin (PubChem CID: 38904); Cell cycle arrest; Cisplatin (PubChem CID: 441203); DT-13; DT-13 (PubChem CID: 101514160); Drug combination; Gastric cancer cell; Paclitaxel (PubChem CID: 36314); Topotecan (PubChem CID: 60700); Topotecan (TPT). Copyright © 2024 Elsevier B.V. …
WebTaken together, our results support FoxO-1 as one of the key factors promoting sensitivity towards selinexor and the synergistic interaction between cisplatin and selinexor in ovarian carcinoma cells with selected molecular backgrounds, highlighting the need for treatment regimens tailored to the molecular tumor features. Keywords: WebDimethylsulfoxid hat entzündungshemmende ( antiphlogistische) und schmerzlindernde ( analgetische) Eigenschaften. [8] [20] Es findet daher therapeutische Verwendung als perkutanes (lat. durch die Haut) Arzneimittel zur Behandlung lokaler Schmerzzustände (beispielsweise bei Sportverletzungen oder rheumatischen Beschwerden).
WebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services.
WebC2210000 Cisplatin European Pharmacopoeia (EP) Reference Standard Synonym (s): cis-Diammineplatinum (II) dichloride, cis-Dichlorodiammine platinum (II), cis-Platinum (II) diammine dichloride, Cisplatin Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 Molecular Weight: 300.05 EC Number: 239-733-8 MDL number: MFCD00011623 … how do you host the world cupWebChemical Name. cis-Diaminodichloroplatinum. Biological Activity. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis. phone accessories wholesale in ukWebCisplatin is an antineoplastic agent that is FDA approved for the treatment of metastatic testicular tumors, metastatic ovarian tumors, and advanced bladder cancer. There is a Black Box Warning for this drug as shown here. Common adverse reactions include anemia, leukopenia, and thrombocytopenia . Adult Indications and Dosage how do you house train a chihuahuaWebCisplatin is approved to be used alone or with other drugs to treat: Bladder cancer. It is used alone in patients with advanced cancer that cannot be treated with other therapies, … how do you host a serverWebCisplatin is one of the most emetogenic chemotherapy agents, but this is managed with prophylactic antiemetics (e.g. ondansetron, granisetron, etc.) in combination with … how do you house train a puppy fastWeb1152 rows · Jun 13, 2005 · Cisplatin is a platinum based chemotherapy agent used to … phone accessories stores in phoenix azWebJul 12, 2024 · Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in … how do you house train a dog