Web28 mag 2024 · Background: In the phase 3 JAVELIN Bladder 100 trial, avelumab 1L maintenance + best supportive care (BSC) significantly prolonged overall survival (OS) … WebBackground. In the phase 3 JAVELIN Bladder 100 trial (NCT02603432), avelumab (anti–PD-L1 IgG1 antibody) 1L maintenance + BSC significantly prolonged overall survival (OS) vs BSC alone in patients (pts) with advanced UC without disease progression with 1L induction chemotherapy in all randomized pts and pts with PD-L1+ tumors.
Maintenance avelumab - UROONCO Bladder Cancer
WebBackground: Platinum-based chemotherapy is an active 1L regimen for advanced UC; however, progression-free survival (PFS) and overall survival (OS) are generally short because of chemotherapy resistance. This randomized, phase 3 trial (JAVELIN Bladder 100; NCT02603432) evaluated avelumab (anti–PD-L1) as maintenance therapy following … WebBackground: The phase 3 JAVELIN Bladder 100 trial showed significantly prolonged overall survival (OS) with avelumab as first-line (1L) maintenance therapy + best supportive care (BSC) vs BSC alone in patients with advanced urothelial carcinoma (UC) that had not progressed with 1L platinum-containing chemotherapy. Efficacy and safety were … plantuml note on link
Avelumab first-line maintenance in locally advanced or ... - PubMed
WebConclusion: Avelumab 1L maintenance treatment showed a favorable benefit-risk balance in Japanese patients, supporting avelumab 1L maintenance as a new standard of care in … Web22 ott 2024 · Here, we report phase 1b data from the multicohort JAVELIN Solid Tumor trial (NCT01772004) in pts with aRCC treated with avelumab monotherapy in either the 1L or … WebDesigned to make a definite style statement in any space, the ultra-slim Lenovo Q27q-1L is a perfect blend of elegance and functionality. No matter how you look at it, the Lenovo Q27q-1L perfectly projects the vibrancy of colors on its In-Plane Switching (IPS) display. Paired with dual speakers, the Lenovo Q27q-1L leverages both the audio and visuals for … plantura meisenknödel